12 Malayalam films of 2010 ranked by box office. #1: Marykkundoru Kunjaadu (₹22.5 crore).
| # | Film | Lead | Director | Budget | Box office | Multiple |
|---|---|---|---|---|---|---|
| 1 | Marykkundoru Kunjaadu | Shafi | ₹3.5 crore | ₹22.5 crore | 6.43x | |
| 2 | Shikkar | M. Padmakumar | ₹3.5 crore | ₹12 crore | 3.43x | |
| 2 | Happy Husbands | Saji Surendran | ₹6 crore | ₹12 crore | 2.00x | |
| 4 | In Ghost House Inn | Lal | ₹2.5 crore | ₹8 crore | 3.20x | |
| 5 | Kaaryasthan | Thomson K Thomas | ₹2.5 crore | ₹4.5 crore | 1.80x | |
| 6 | A Boy Called Elsamma | Lal Jose | ₹1.8 crore | ₹4 crore | 2.29x | |
| Pokkiri Raja | Vyshakh | $1.3 million | $4.7 million | 3.73x | ||
| Best Actor | Martin Prakkat | $700,000 | $3.9 million | 5.56x | ||
| Aagathan | Kamal | $822,000 | $1.2 million | 1.46x | ||
| Pranchiyettan & the Saint | Ranjith | $385,320 | $1.1 million | 2.91x | ||
| Malarvaadi Arts Club | Vineeth Sreenivasan | ₹1.8 crore | $1 million | |||
| Mummy & Me | Jeethu Joseph | $225,000 | $750,000 | 3.33x |
Figures are shown in the currency they were reported in (Wikipedia, Wikidata or TMDB); no conversion.