16 Tamil films of 2010 ranked by box office. #1: Enthiran (₹283 crore).
| # | Film | Lead | Director | Budget | Box office | Multiple |
|---|---|---|---|---|---|---|
| 1 | Enthiran | S. Shankar | ₹150 crore | ₹283 crore | 1.89x | |
| 2 | Singam | Hari | ₹15 crore | ₹90 crore | 6.00x | |
| 3 | Sura | S. P. Rajkumar | ₹15 crore | |||
| 4 | Kalavani | A. Sarkunam | ₹1.5 crore | ₹5 crore | 3.33x | |
| 5 | Ambasamudram Ambani | ₹75 lakh | ₹1 crore | 1.33x | ||
| Aayirathil Oruvan | Selvaraghavan | $7.5 million | $20 million | 2.67x | ||
| Vinnaithaandi Varuvaayaa | Gautham Vasudev Menon | $3 million | $12 million | 4.00x | ||
| Milaga | Ravi Mariya | $3 million | $10 million | 3.33x | ||
| Chikku Bukku | V. Manikandan | ₹6.5 crore | $10 million | |||
| Thillalangadi | Mohan Raja | $3.3 million | $10 million | 3.03x | ||
| Raavanan | Mani Ratnam | $5.2 million | $9.7 million | 1.87x | ||
| Angadi Theru | Vasanthabalan | $600,000 | $2 million | 3.33x | ||
| Vandae Maatharam | T. Aravind | $2.4 million | $1.6 million | 0.67x | ||
| Va | Shiva | Gayatri | ₹4.5 crore | $1.5 million | ||
| Aaranya Kaandam | Thiagarajan Kumararaja | ₹5.2 crore | $1 million | |||
| Crayon | Dean A. Burhan | MYR 1.3 million | MYR 53,000 | 0.04x |
Figures are shown in the currency they were reported in (Wikipedia, Wikidata or TMDB); no conversion.