24 Telugu films of 2021 ranked by box office. #1: Pushpa: The Rise (₹350 crore).
| # | Film | Lead | Director | Budget | Box office | Multiple |
|---|---|---|---|---|---|---|
| 1 | Pushpa: The Rise | Allu Arjun | Sukumar | ₹200 crore | ₹350 crore | 1.75x |
| 2 | Akhanda | Nandamuri Balakrishna | Boyapati Srinu | ₹60 crore | ₹150 crore | 2.50x |
| 3 | Vakeel Saab | Pawan Kalyan | Venu Sree Raam | ₹80 crore | ₹137.7 crore | 1.72x |
| 4 | Love Story | Naga Chaitanya | Sekhar Kammula | ₹30 crore | ₹95 crore | 3.17x |
| 5 | Krack | Ravi Teja | Gopichand Malineni | ₹70.6 crore | ||
| 6 | Shyam Singha Roy | Nani | Rahul Sankrityan | ₹50 crore | ₹65 crore | 1.30x |
| 7 | Major | Adivi Sesh | ₹32 crore | ₹64 crore | 2.00x | |
| 8 | Most Eligible Bachelor | Akhil Akkineni | Bhaskar | ₹51 crore | ||
| 9 | Red | Kishore Tirumala | ₹35.6 crore | |||
| 10 | Rang De | Nithiin | Venky Atluri | ₹30 crore | ₹28.8 crore | 0.96x |
| 11 | Seetimaarr | Gopichand | Sampath Nandi | ₹12 crore | ₹18.9 crore | 1.57x |
| 12 | SR Kalyanamandapam | Kiran Abbavaram | Sridhar Gade | ₹14.9 crore | ||
| 13 | Check | Chandra Sekhar Yelati | ₹14 crore | |||
| 14 | Zombie Reddy | Teja Sajja | Prasanth Varma | ₹4 crore | ₹12 crore | 3.00x |
| 15 | Raja Raja Chora | Sree Vishnu | Hasith Goli | ₹11.2 crore | ||
| 16 | Paagal | Vishwak Sen | Naresh Kuppili | ₹9.6 crore | ||
| 17 | Naandhi | Allari Naresh | Vijay Kanakamedala | ₹6 crore | ₹9.5 crore | 1.58x |
| 18 | Wild Dog | Nagarjuna Akkineni | Ahishor Solomon | ₹6 crore | ₹7 crore | 1.17x |
| 19 | Chaavu Kaburu Challaga | Kartikeya Gummakonda | Koushik Pegallapati | ₹5.4 crore | ||
| 20 | A1 Express | Lavanya Tripathi | Dennis Jeevan Kanukolanu | ₹5 crore | ||
| 21 | Anubhavinchu Raja | Raj Tarun | Srinivas Gavireddy | ₹5 crore | ||
| 22 | Lakshya | Naga Shaurya | Santosh Jagarlapudi | ₹4.5 crore | ||
| 23 | Mosagallu | Vishnu Manchu | Jeffrey Gee Chin | ₹51 crore | ₹50 lakh | 0.01x |
| 24 | Madam Chief Minister | Richa Chadha | Subhash Kapoor | ₹5 lakh |
Figures are shown in the currency they were reported in (Wikipedia, Wikidata or TMDB); no conversion.