| Director | Rob Minkoff |
|---|---|
| Genre | comedy film, family film, film based on literature |
| Runtime | 77 min |
| Country | United States |
| Budget | $120 million |
| Box office | $170 million |
Three years after being adopted by the Littles and defeating Smokey, Stuart Little has settled into family life with his parents, older brother George, and baby sister Martha, who has yet to say her first words. Stuart is becoming tired of his adoptive mother Eleanor's overprotectiveness due to his small size, and is finding himself lonely when George would rather play with his own friend, Will. When playing by himself, Stuart accidentally wrecks George's toy plane while trying to fix it, prompting George to furiously throw it into a trash can at Eleanor's request due to it being much too dangerous. Stuart is upset about the situation, but his adoptive father Frederick tells him there is a "silver lining" to every hard situation, and encourages him to find a new friend of his own.
When driving home from school in his roadster, Stuart meets Margalo, a canary who falls into his car. Margalo states she has injured her wing being chased by a predatory Falcon, and Stuart takes her home to recover. Unbeknownst to the Littles, Margalo is in fact physically healthy, and is working for Falcon to steal precious items from households. However, she soon bonds with the Littles, and feels immense guilt over what she is planning to do.
Falcon threatens Stuart's life if she does not complete their plan. Margalo steals Eleanor's ring, prompting Stuart to venture down the Littles' kitchen drain in an unfruitful attempt to find it again. He soon finds himself in trouble, but Margalo rescues him; realizing the danger she is putting him in, she leaves the next morning. Stuart becomes convinced that Falcon has kidnapped her, and sets off to find her with Snowbell, the family cat, while George conducts a series of lies to their parents to explain Stuart's absence.
To find Falcon, Stuart and Snowbell seek out Monty, who tells them that Falcon lives at the top of the Pishkin Building, and warns that he is extremely dangerous. Stuart uses a balloon to fly to the top of the building where he finds Falcon and Margalo. Falcon reveals the truth about Margalo and Eleanor's ring which shocks Stuart, but Margalo insists that their friendship was genuine. Stuart asks her to prove it by leaving with him, angering Falcon. Falcon then drops Stuart off the building and traps Margalo in an empty paint can. Stuart however lands in a garbage truck and is taken to a garbage barge out at sea. Initially devastated, Stuart soon finds his silver lining by rediscovering and repairing George's broken toy plane, which he uses to fly back to land. Meanwhile, George is reprimanded by his parents for his deception - in which he told them that Stuart had been staying at Will's house to rehearse as part of a play only to be exposed by Will's mother who was unaware - and interrogated on Stuart's true whereabouts. George reveals where Stuart is, prompting the family to head out and look for him.
Back at the Pishkin Building, Snowbell makes his way to the top and frees Margalo from the paint can, only to become trapped in it himself. Margalo ends her allegiance with Falcon, and flies away with Eleanor's ring, prompting Falcon to give chase. Stuart arrives in his toy plane, and a furious chase occurs through Manhattan, with the Littles and Snowbell following from behind. Stuart ultimately wins the battle by using the ring to blind Falcon's vision, before jumping out from the plane and allowing it to crash into Falcon as he falls into a trash can and is presumably eaten by Monty. The day saved, Frederick and Eleanor forgive Stuart for running away, George for lying to them, and Margalo for taking the ring, telling them they are extremely proud of them for their bravery. Later, Margalo fulfills her dream of flying south for the winter, planning on returning to the Little household in the spring. Martha stuns everyone by using her first words, "Bye, bye, birdie." to say goodbye to Margalo.