Prabhu and Santhanam have appeared together in 11 films between 1972 and 2015, with a combined box office of ₹8 crore. Every shared film with year, roles and gross, plus who else each works with most.
| Year | Film | Box office |
|---|---|---|
| 1972 | உனக்கும் எனக்கும் | |
| 2006 | Unakkum Enakkum | |
| 2007 | Billa | |
| 2008 | Kuselan | ₹8 crore |
| 2008 | Silambattam | |
| 2009 | Malai Malai | |
| 2010 | Maanja Velu | |
| 2010 | Thillalangadi | $10 million |
| 2012 | Mirattal | |
| 2013 | All in All Azhagu Raja | |
| 2015 | Aambala |
Prabhu also often with: Prabhu Ganesan (115), Nassar (27), Vijayakumar (27), Manorama (26), Senthil (26)
Santhanam also often with: N. Santhanam (53), Manobala (34), Mayilsamy (24), Nassar (20), M. S. Bhaskar (17)