Mammootty and Seema have appeared together in 53 films between 1976 and 2022, with a combined box office of ₹52 crore. Every shared film with year, roles and gross, plus who else each works with most.
| Year | Film | Box office |
|---|---|---|
| 1976 | Sindooram | |
| 1981 | Ahimsa | |
| 1981 | Sphodanam | |
| 1982 | Chiriyo Chiri | |
| 1982 | Innalenkil Nale | |
| 1982 | Katha | |
| 1982 | Komaram | |
| 1982 | Komaran | |
| 1982 | Sandhyakku Virinja Poovu | |
| 1982 | Sindoora Sandhyakku Mounam | |
| 1982 | Thadaakam | |
| 1983 | America America | |
| 1983 | Iniyengilum | |
| 1983 | Maniyara | |
| 1983 | Mansoru Maha Samudram | |
| 1983 | Marakkillorikkalum | |
| 1983 | Nanayam | |
| 1983 | Oru Madapravinte Katha | |
| 1983 | Oru Mukham Pala Mukham | |
| 1983 | Rugma | |
| 1984 | Aalkkoottathil Thaniye | |
| 1984 | Adiyozhukkukal | |
| 1984 | Aksharangal | |
| 1984 | Anubandham | |
| 1984 | Athirathram | |
| 1984 | Kanamarayathu | |
| 1984 | Kodathy | |
| 1984 | Lakshmana Rekha | |
| 1984 | Manithali | |
| 1984 | Onnanu Nammal | |
| 1984 | Sandarbham | |
| 1984 | Sandyakkenthinu Sindhooram | |
| 1984 | Thirakkil Alppa Samayam | |
| 1985 | Aa Neram Alppa Dooram | |
| 1985 | Anubandham | |
| 1985 | Idanilangal | |
| 1985 | Karimpinpoovinakkare | |
| 1985 | Manya Mahajanangale | |
| 1986 | Aavanazhi | |
| 1986 | Ee Kaikalil | |
| 1986 | Gandhinagar 2nd Street | |
| 1986 | Vartha | |
| 1987 | Adimakal Udamakal | |
| 1987 | Ithrayum Kaalam | |
| 1987 | Naalkavala | |
| 1988 | 1921 | ₹2 crore |
| 1988 | Mattoral | |
| 1988 | Mukthi | |
| 1988 | Sangham | |
| 1988 | Vicharana | |
| 1989 | Mahayanam | |
| 2006 | Prajapathi | |
| 2022 | Kaduva | ₹50 crore |
Mammootty also often with: Sukumari (103), Jagathy Sreekumar (92), Nedumudi Venu (77), Janardhanan (70), Lalu Alex (70)
Seema also often with: I. V. Sasi (41), Mohanlal (33), Sukumari (29), Sankaradi (28), Balan K. Nair (25)