Mammootty and Santhosh have appeared together in 12 films between 1976 and 2005, with a combined box office of ₹2 crore. Every shared film with year, roles and gross, plus who else each works with most.
| Year | Film | Box office |
|---|---|---|
| 1976 | Sindooram | |
| 1983 | Pinnilavu | |
| 1984 | Itha Innu Muthal | |
| 1984 | Sandyakkenthinu Sindhooram | |
| 1985 | Angadikkappurathu | |
| 1985 | Eeran Sandhya | |
| 1985 | Iniyum Kadha Thudarum | |
| 1988 | 1921 | ₹2 crore |
| 1992 | Kauravar | |
| 1993 | Dhruvam | |
| 1993 | Sainyam | |
| 2005 | Bus Conductor |
Mammootty also often with: Sukumari (103), Jagathy Sreekumar (92), Nedumudi Venu (77), Janardhanan (70), Lalu Alex (70)
Santhosh also often with: Janardhanan (12), Mohanlal (12), Jagathy Sreekumar (11), Sukumari (11), Jagadish (10)