Thilakan and Santhakumari have appeared together in 16 films between 1980 and 2004. Every shared film with year, roles and gross, plus who else each works with most.
| Year | Film | Box office |
|---|---|---|
| 1980 | Sathyam | |
| 1983 | Prem Nazirine Kanmanilla | |
| 1983 | Sesham Kazhchayil | |
| 1984 | Aattuvanchi Ulanjappol | |
| 1986 | Gandhinagar 2nd Street | |
| 1986 | Ice Cream | |
| 1988 | Kudumbapuranam | |
| 1989 | Kireedam | |
| 1989 | Season | |
| 1992 | Ayalathe Adheham | |
| 1993 | Chenkol | |
| 1993 | Sagaram Sakshi | |
| 1997 | Manikya Koodaram | |
| 1998 | Meenathil Thalikettu | |
| 1998 | Veendum Chila Veettukaryangal | |
| 2004 | Sathyam |
Thilakan also often with: Jagathy Sreekumar (94), Sukumari (73), Mammootty (70), Nedumudi Venu (70), Innocent (57)
Santhakumari also often with: Jagathy Sreekumar (32), Mammootty (30), Sukumari (30), Mohanlal (28), Sankaradi (27)