| 2024 | Better Man | actor | $22.5 million |
| 2023 | The Rooster | actor | |
| 2022 | Lynch/Oz | actor | $68,987 |
| 2021 | Demented | director | |
| 2021 | The Velvet Underground | actor | |
| 2017 | 2:22 | actor | $3.9 million |
| 2017 | Mansfield 66/67 | actor | |
| 2017 | Queercore – How to Punk a Revolution | actor | |
| 2017 | Three Summers | actor | |
| 2015 | Tab Hunter Confidential | actor | |
| 2015 | The 1000 Eyes of Dr. Maddin | actor | |
| 2014 | Suburban Gothic | actor | |
| 2013 | I Am Divine | actor | $81,497 |
| 2013 | The Sarnos – A Life in Dirty Movies | actor | |
| 2012 | Excision | actor | |
| 2012 | Mansome | actor | $18,395 |
| 2012 | The Cage Door Is Always Open | actor | |
| 2011 | Mangus! | actor | |
| 2011 | These Amazing Shadows | actor | |
| 2010 | Beautiful Darling | actor | |
| 2010 | Blank City | actor | |
| 2010 | William S. Burroughs: A Man Within | actor | |
| 2009 | For the Love of Movies: The Story of American Film Criticism | actor | |
| 2009 | It Came from Kuchar | actor | |
| 2007 | Hairspray | actor | $203.5 million |
| 2007 | The Junior Defenders | actor | |
| 2006 | Fabulous! The Story of Queer Cinema | actor | |
| 2006 | Jack Smith and the Destruction of Atlantis | actor | |
| 2006 | Jackass Number Two | actor | $84.6 million |
| 2006 | This Film Is Not Yet Rated | actor | $339,609 |
| 2006 | This Filthy World | actor | |
| 2005 | Inside Deep Throat | actor | $709,832 |
| 2005 | Midnight Movies: From the Margin to the Mainstream | actor | |
| 2005 | That Man: Peter Berlin | actor | $55,398 |
| 2004 | A Dirty Shame | director | $1.9 million |
| 2004 | Plagues & Pleasures on the Salton Sea | actor | $53,471 |
| 2004 | Seed of Chucky | actor | $24.8 million |
| 2003 | Abby Singer | actor | |
| 2002 | Blood Feast 2: All U Can Eat | actor | |
| 2002 | The Cockettes | actor | $220,165 |
| 2001 | Pie in the Sky: The Brigid Berlin Story | actor | |
| 2000 | Cecil B. Demented | actor | $2 million |
| 2000 | Cecil B. Demented | director | $2 million |
| 2000 | In Bad Taste | actor | |
| 1999 | Sweet and Lowdown | actor | $4.2 million |
| 1999 | The Sugar Factory | actor | A$11,109 |
| 1998 | Divine Trash | actor | $39,842 |
| 1998 | Pecker | director | $2.3 million |
| 1998 | The Real Macaw | actor | $741,876 |
| 1998 | Welcome to Hollywood | actor | |
| 1996 | Ballyhoo: The Hollywood Sideshow! | actor | |
| 1994 | Ebbtide | actor | |
| 1994 | Serial Mom | director | $7.8 million |
| 1990 | Cry-Baby | director | $8.3 million |
| 1990 | Heaven Tonight | actor | |
| 1989 | Homer and Eddie | actor | |
| 1988 | Boulevard of Broken Dreams | actor | A$126,359 |
| 1988 | Grievous Bodily Harm | actor | $82,267 |
| 1988 | Hairspray | director | $8.3 million |
| 1987 | Bushfire Moon | actor | A$493,871 |
| 1987 | Going Sane | actor | |
| 1986 | Something Wild | actor | $8.4 million |
| 1985 | Divine Waters | actor | |
| 1985 | I Can't Get Started | actor | |
| 1985 | The Perfectionist | actor | |
| 1983 | High Country | actor | |
| 1982 | Attack Force Z | actor | $88,000 |
| 1981 | Polyester | director | $1.1 million |
| 1980 | Breaker Morant | actor | $4.7 million |
| 1978 | Weekend of Shadows | actor | A$61,000 |
| 1977 | Desperate Living | director | |
| 1977 | Summerfield | actor | |
| 1977 | The Getting of Wisdom | actor | A$982,000 |
| 1976 | Edith's Shopping Bag | actor | |
| 1976 | Eliza Fraser | actor | A$2.2 million |
| 1975 | End Play | actor | A$800,000 |
| 1975 | Love Letter to Edie | actor | |
| 1974 | Female Trouble | director | |
| 1972 | Pink Flamingos | actor | $1.9 million |
| 1972 | Pink Flamingos | director | $1.9 million |
| 1970 | Multiple Maniacs | director | $33,036 |
| 1970 | The Diane Linkletter Story | director | |
| 1969 | Mondo Trasho | director | |
| 1969 | Mondo Trasho | actor | |
| 1968 | Eat Your Makeup | director | |
| 1961 | Something Wild | actor | |
| 1961 | The Mystery of the Hansom Cab | actor | |
John Waters: 84 films, 1961–2024, English cinema, total box office $392.8 million across 29 films. Filmography with box office, frequent collaborators and collaboration network on TinyFalcon.