Prakash Raj and Santhanam have appeared together in 18 films between 1969 and 2017. Every shared film with year, roles and gross, plus who else each works with most.
| Year | Film | Box office |
|---|---|---|
| 1969 | Thirudan | |
| 2002 | Kadha | |
| 2002 | Kadhal Azhivathillai | |
| 2006 | Idhaya Thirudan | |
| 2007 | Veerappu | |
| 2007 | Viyabari | |
| 2008 | Arai En 305-il Kadavul | |
| 2008 | Santosh Subramaniam | |
| 2009 | Malai Malai | |
| 2009 | Thoranai | |
| 2010 | Chutti Chathan | |
| 2010 | Theeradha Vilaiyattu Pillai | |
| 2011 | Badrinadh | |
| 2011 | Vaanam | |
| 2012 | Saguni | |
| 2013 | Thillu Mullu 2 | |
| 2015 | JK Enum Nanbanin Vaazhkai | |
| 2017 | Kalavaadiya Pozhuthugal |
Prakash Raj also often with: Brahmanandam (93), Tanikella Bharani (61), Nassar (59), M. S. Narayana (49), Raghu Babu (43)
Santhanam also often with: Manobala (34), Mayilsamy (24), Nassar (20), M. S. Bhaskar (18), Rajendran (18)