Santhanam and Rajendran have appeared together in 18 films between 2010 and 2025, with a combined box office of ₹189.3 crore. Every shared film with year, roles and gross, plus who else each works with most.
| Year | Film | Box office |
|---|---|---|
| 2010 | Boss Engira Bhaskaran | |
| 2011 | Thambikottai | |
| 2013 | Raja Rani | |
| 2013 | Singam II | ₹136 crore |
| 2015 | Nanbenda | |
| 2015 | Vaaliba Raja | |
| 2016 | Dhilluku Dhuddu | ₹12 crore |
| 2017 | Enakku Vaaitha Adimaigal | |
| 2019 | A1 | |
| 2019 | Dhilluku Dhuddu 2 | |
| 2020 | Biskoth | |
| 2021 | Dikkiloona | |
| 2021 | Parris Jeyaraj | |
| 2023 | 80s Buildup | |
| 2023 | DD Returns | ₹41.3 crore |
| 2023 | Kick | |
| 2024 | Vadakkupatti Ramasamy | |
| 2025 | DD Next Level |
Santhanam also often with: Manobala (34), Mayilsamy (24), Nassar (20), M. S. Bhaskar (18), Prakash Raj (18)
Rajendran also often with: Yogi Babu (44), Manobala (36), Mayilsamy (23), Swaminathan (22), Aadukalam Naren (21)